A ratiometric naphthalimide sensor for live cell imaging of copper(I).

نویسندگان

  • Cristina Satriano
  • Giuseppe Trusso Sfrazzetto
  • Maria Emanuela Amato
  • Francesco P Ballistreri
  • Agata Copani
  • Maria Laura Giuffrida
  • Giuseppe Grasso
  • Andrea Pappalardo
  • Enrico Rizzarelli
  • Gaetano A Tomaselli
  • Rosa Maria Toscano
چکیده

A new naphthalimide derivative bearing a tetrathia-azacrown for high affinity and selective binding to Cu(+) was synthesised. Copper recognition properties in solution were evaluated using (1)H NMR and fluorescence spectroscopy. Live cell imaging by confocal microscopy highlighted the capabilities of the new sensor for the two-wavelength detection of intracellular monovalent copper in neuronal cells.

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عنوان ژورنال:
  • Chemical communications

دوره 49 49  شماره 

صفحات  -

تاریخ انتشار 2013